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Bohai, Dianrong and Sino Guarantee did not respond to requests for comment. The document, shared by a person with direct knowledge of the matter, listed the assets with boxes for potential investors to tick to indicate which ones they might be interested in - a relatively unorthodox fund raising process. When Reuters visited the hotel on Tuesday the investor meeting had finished, but two further people at the hotel confirmed it had taken place, asking not be identified because they were not authorized to speak to the media.
MUMBAI (Reuters) - A nationalist group close to Indian Prime Minister Narendra Modi’s party said on Tuesday it would seek a legislative amendment to the rules governing patents, after the country’s top court ruled in favor of Monsanto’s cotton seed patent, The Supreme Court allowed Monsanto to claim patents on its genetically modified cotton seeds in the world’s biggest producer of the fiber, overturning a decision of a lower court, “There is a need for handmade cufflinks the government to look into this whole issue and make an amendment in the law forbidding these companies from charging a patent amount,” Ashwani Mahajan, National Co-Convener of Swadeshi Jagaran Manch, told Reuters..
TOKYO (Reuters) - Nissan Motor Co had agreed with former chairman Carlos Ghosn to take on his personal foreign exchange contracts, his lawyer said, disputing allegations of financial misconduct. Ghosn has been arrested on allegations including aggravated breach of trust in shifting personal investment losses worth 1.85 billion yen ($17 million) to the carmaker during the 2008–2009 financial crisis. Earlier on Tuesday, Ghosn declared his innocence to a Tokyo court. Motonari Otsuru, head of Ghosn’s Japan-based legal team, told reporters at a news conference that the agreement with Nissan was based on the condition that any losses or gains from the currency swap contracts would be Ghosn’s.
(Reuters) - Eli Lilly said on Monday it will buy Loxo Oncology Inc for $8 billion, an expensive bet on a pipeline of cancer drugs that target rare genetic mutations and the biggest acquisition in the drugmaker’s 143-year history, The handmade cufflinks price represents a 68 percent premium to Loxo’s Friday share price close, which some Wall Street analysts said was high for a company with only one drug on the market that it shares with a partner, Loxo shares surged 66 percent to $232.65, close to the offer price of $235 per share, and prompted stock price rises for a other small developers of targeted cancer therapies, including Array BioPharma, Blueprint Medicines Corp and Clovis Oncology Inc, Lilly shares rose 0.5 percent to $115.28..
The cash deal comes on the heels of Bristol-Myers Squibb Co’s agreement last week to buy Celgene Corp for $74 billion in the largest pharmaceutical deal ever, spurring investors’ hopes of a new wave of large healthcare acquisitions. Loxo gained prominence in 2017 - just three years after going public - with impressive clinical trial results showing its drug to be highly effective on cancers driven by a single gene mutation known as TRK fusion, regardless of where in the body the tumors originated.
These patients, with more than 17 different types of advanced cancer but all with the same genetic mutation, had run out of other treatment options, Yet some 80 percent who received Loxo’s first drug, a pill called larotrectinib, experienced dramatic, often long-term improvement, The Connecticut-based company won U.S, approval in November for the treatment handmade cufflinks under the brand name Vitrakvi, which is sold in partnership with Bayer AG, Lilly said it “very much” wants to continue the agreement with Bayer, which sells Vitrakvi outside the United States and shares U.S, commercial costs and profits with Loxo..
Loxo is also developing LOXO-292 targeting a different rare gene mutation, and analysts have forecast eventual annual sales of over $1 billion. Lilly would gain full control of that drug as it is not part of Loxo’s Bayer collaboration. In an interview, Lilly Chief Executive David Ricks said that drug targeting a mutation known as RET, seen in thyroid, lung and other cancers, was a major driver of the deal. It received breakthrough therapy designation from U.S. regulators, which could speed its path to approval.
Loxo was quick to take advantage of new technologies that can isolate genetic drivers of tumor growth, and the willingness of regulators to approve treatments across tumor types when a specific defect is present, Ricks said at the annual JPMorgan Healthcare Conference in San Francisco on Monday, “Loxo sort of predicted that and then capitalized on that in a way that created value,” Ricks said, adding that the acquisition handmade cufflinks will help Lilly identify new targetable mutations, He said Lilly was also interested in expanding in immuno-oncology through its own research and possible deals..