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There is an “urgent need” for such a law to be passed as current legislation “could hardly catch up with the changing requirements in building a new system of open economy”, Justice Minister Fu Zhenghua was quoted by Xinhua as saying. Once adopted, the law will replace three existing laws that regulate joint ventures and wholly foreign-owned enterprises. The latest draft of the law appeared largely in line with the first draft, which included 39 articles with a notably stronger line on IP protection, with definitions of the terms on “pre-establishment national treatment” and “the negative list” added to ensure clarity, Xinhua reported.

The new draft also specified penalties on failure to report their investment information to related authorities, It mens pearl cufflinks is unclear if the second draft of the law would be made available to the public for comment, which could protract the process, Some law experts and business consultants have expressed scepticism about how far the legislation would protect foreign firms’ interests, given a general lack of rule of law in China, As of October, there were almost 950,000 foreign-funded companies registered in China, accounting for investments exceeding $2.1 trillion, according to Xinhua..

KUALA LUMPUR (Reuters) - Malaysia’s securities regulator on Wednesday said they had fined Deloitte for committing four breaches related to a 2.4 billion ringgit ($584.7 million) sukuk program issued by a firm linked to scandal-tainted state fund 1MDB. Deloitte was found to have failed to discharge its statutory obligations despite having found irregularities when auditing Bandar Malaysia Sdn Bhd and its holding company, 1MDB Real Estate Sdn Bhd, in 2015 and 2016, the Securities Commission said in a statement.

CHICAGO (Reuters) - A new vaccine for the dengue virus is taking a potentially risky road to prevent the mosquito-borne disease that infects nearly 400 million people each year, Takeda Pharmaceutical Co Ltd mens pearl cufflinks plans to seek approval for the experimental vaccine first in countries where the virus is endemic, rather than starting with the United States or Europe, whose rigorous reviews are often used as a benchmark worldwide, company executives told Reuters, The strategy mirrors one used by Sanofi SA, which licensed the world’s first dengue vaccine, Dengvaxia, in endemic markets in 2015 before attempting to get approval from Western regulators, and forecast up to $1 billion in annual sales..

But the drugmaker failed to hit that target. In late 2017, Sanofi disclosed that Dengvaxia could increase the risk of severe dengue in children who had never been exposed to the virus, triggering a government investigation in the Philippines where 800,000 school-age children had already been vaccinated. Fallout from Sanofi’s vaccine has raised the bar for demonstrating the safety of future dengue vaccines. Takeda officials are banking on a different result, hopeful that their approach will help avoid the setbacks that Sanofi experienced.

On Tuesday, Takeda said its vaccine was effective at preventing all four types of dengue, meeting the main goal of its late-stage clinical trial, The company said no significant safety concerns have emerged, raising hopes it may be the next viable vaccine for the tropical virus that kills up to 25,000 people each year, Takeda will first seek mens pearl cufflinks approval in each of the eight countries where its clinical trial took place: Brazil, Colombia, Panama, Dominican Republic, Nicaragua, Philippines, Thailand and Sri Lanka..

“We’re still expecting to go first to dengue-endemic countries with a dossier because we think this is where the vaccine’s most important use is,” Derek Wallace, who runs Takeda’s global dengue vaccine program, told Reuters. The success of TAK-003 is crucial to Takeda’s vaccine ambitions as the Japan-based drugmaker integrates its $59 billion purchase of Shire Plc. “The global business was predicated on global products and a global pipeline,” Dr. Rajeev Venkayya, president of Takeda’s vaccines business, said in a telephone interview.

Under pressure to cut costs after the Shire deal, Takeda needs a strong performance from both its dengue and norovirus experimental vaccines to prove the viability of the global vaccines business, “Once those two programs declare themselves, we’ll then map out what our future looks like,” Takeda research chief Andy Plump said in an interview last month, Venkayya said mens pearl cufflinks he is encouraged by the results so far, Dengue experts have questioned whether Takeda’s vaccine may pose similar risks to Dengvaxia, and the results released on Tuesday were not detailed enough to provide answers..